:FISH used to do chromosome painting to make a comparison between two species or varieties by using DNA from entire chromosomes or even the entire genome of one species as a probe on the other. In this way, Chromosomal abnormalities can be identified and evolutionary relations can be deduced.
:FISH can be used to identify microorganisms. This last application is nowadays widely used in Microbial Ecology. For example in Biofilm.
:FISH has also application in clinical studies. To detect if a patient is infected with a suspected pathogen
: FISH also evolved into a core technique spanning many areas of diagnosis and research, including cancer cytogenetics, prenatal screening of chromosomal aberrations, molecular pathology and developmental molecular biology.
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